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Clobetasol is a prescription drug. It comes as a topical cream, lotion, spray, solution, foam, ointment, and gel. It also comes as a shampoo. Clobetasol topical cream comes in two forms: regular cream and emollient cream. (Emollient creams are moisturizing treatments.) The regular form is available as the brand-name drug Impoyz. The regular and emollient forms are available as generic drugs. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Why it’s usedBoth forms of clobetasol topical cream are used to treat inflammation and itching from various skin conditions. They’re also used to treat moderate to severe plaque psoriasis. Clobetasol topical cream may be used as part of a combination therapy. This means you may need to take it with other medications. How it worksClobetasol belongs to a class of drugs called topical corticosteroids. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Clobetasol works by decreasing your body’s response to inflammation. It also reduces the activity of your immune system. This prevents inflammation and itching and treats your skin condition. Clobetasol topical cream doesn’t cause drowsiness. However, it can cause other side effects. More common side effectsThe most common side effects of clobetasol include:
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist. Serious side effectsCall your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Clobetasol topical cream can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist. Examples of drugs that can cause interactions with clobetasol are listed below: CorticosteroidsDo not take these drugs with clobetasol. Doing so can cause dangerous effects in your body. Examples of these drugs include:
Taking clobetasol topical cream with other corticosteroids may cause the steroids in your body to build up to dangerous levels. This can cause Cushing’s syndrome and high blood sugar. It may also stop your adrenal glands from working well. Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. This information is not a substitute for medical advice. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Clobetasol topical cream comes with several warnings. Allergy warningClobetasol may cause allergic skin reactions that are difficult to heal. Your doctor may do a skin patch test to check if you have an allergic skin reaction. Symptoms of a skin reaction can include:
This drug may also cause severe allergic reactions. Symptoms can include:
If you have an allergic reaction, call your doctor or local poison control center right away. If your symptoms are severe, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal (cause death). Drug transfer warningThis drug may transfer to other people if they touch your treated skin. Be sure to wash your hands well with soap and water after you apply it. Warnings for people with certain health conditionsFor people with liver problems: This drug is processed by your liver. If you have severe liver problems, your body may not be able to break down this drug as well. This could cause the drug to build up in your body. This may increase your risk of side effects. Warnings for other groupsFor pregnant women: Clobetasol is a category C pregnancy drug. That means two things:
Talk to your doctor if you’re pregnant or plan to become pregnant. This drug should only be used if the potential benefit justifies the potential risk.youn For women who are breastfeeding: Clobetasol may pass into breast milk and cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication. For seniors: The kidneys, liver, and heart of an older adult may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. Your doctor may start you on a lowered dosage or a different treatment schedule. This can help keep levels of this drug from building up too much in your body. For children: Clobetasol topical cream has not been confirmed as safe and effective for use in children younger than 12 years. Impoyz, the brand-name form of the drug, has not been confirmed as safe and effective for use in children younger than 18 years. This drug may cause children’s adrenal glands to work more slowly. It may cause children to develop Cushing’s syndrome, grow more slowly, and gain weight. This drug can also increase brain pressure in children. Your child’s doctor can tell you more. This dosage information is for clobetasol topical cream. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
Dosage for inflammation and itching from skin conditionsGeneric: Clobetasol
Adult dosage (ages 18–64 years) Apply this drug to the affected areas of your skin twice per day. Rub it in carefully. Child dosage, emollient cream only (ages 12–17 years) Apply this drug to the affected areas of your child’s skin twice per day. Rub it in carefully. Child dosage (ages 0–11 years) It hasn’t been confirmed that this drug safe or effective in people younger than 12 years. Senior dosage (ages 65 years and older) The kidneys, liver, and heart of an older adult may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. Your doctor may start you on a lowered dosage or a different treatment schedule. Dosage warnings
Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. This information is not a substitute for medical advice. Always speak with your doctor or pharmacist about dosages that are right for you. Clobetasol topical cream is used for short-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug suddenly or don’t take it at all: Your skin problems may not improve. If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. If you take too much: Clobetasol could reach your blood, which can cause problems. Symptoms of an overdose of this drug can include:
If you think you’ve used too much of this drug, call your doctor or local poison control center. If your symptoms are severe, call 911 or go to the nearest emergency room right away. What to do if you miss a dose: Apply this medication as soon as you remember. If you remember just a few hours before your next scheduled dose, apply it only once. How to tell if the drug is working: The symptoms of your skin condition should get better. Keep these considerations in mind if your doctor prescribes clobetasol topical cream. General
Storage
RefillsA prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. TravelWhen traveling with your medication:
Self-managementYour doctor will tell your how to use this drug. Only use this drug on your skin. Don’t apply it to your face, armpits, or groin areas. Don’t cover the treated areas with a dressing unless your doctor tells you to do so. Clinical monitoringYour doctor may do tests to check how your adrenal glands are working. If your adrenal glands aren’t working well, your doctor may change how often you use this drug. They may also stop your treatment with this drug. There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. What happens if you use clobetasol too much?You're more likely to have a serious side effect if you use clobetasol on a large area of skin for a long time. Using clobetasol for a long time can make your skin thinner or cause stretch marks. Stretch marks are likely to be permanent, but they usually fade over time.
Does clobetasol propionate have side effects?Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: stretch marks, skin thinning/discoloration, acne, extreme/unwanted hair growth, "hair bumps" (folliculitis). Skin infections can become worse when this medication is used.
Who should not use clobetasol?Safety and efficacy have not been established in children younger than 12 years of age and the use of clobetasol topical cream, foam, gel, ointment, or scalp solution is not recommended.
How long does topical clobetasol stay in your system?by Drugs.com
Some researchers have found that suppression of cortisol levels is still apparent 96 hours after topical use of this medicine, which implies that clobetasol can stay in your system for long periods of time, possibly for up to a few weeks.
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