Findings from both meta-analyses support the view that the bacterial strain remains the only probiotic currently available that demonstrates a certain efficacy in tackling colic. Show “With six positive randomised, double-blind and placebo-controlled clinical trials and nine meta-analyses, the proof of L. reuteri Protectis in infant colic is solid,” said Axel Sjöblad, managing director, BioGaia. ”Health care professionals can be reassured that they are suggesting an effective and safe treatment when recommending BioGaia Protectis drops to their patients.” Cranky babies with colicColic refers to the condition that can affect 5% to 40% of infants. It is characterised by inconsolable and excessive crying that can be accompanied by bouts of fussiness and passing of gas. These symptoms contribute to irritability and fussing lasting for at least three hours a day, for as long as three weeks. Triggers for infantile colic remain elusive with theories proposed include overproduction of intestinal gas, forceful intestinal contraction and a lactase deficiency. Theories explaining its onset have also been gut-centric with miscommunication between brain and intestine, hypersensitivity to cow's milk protein and changes in intestinal microbiota put forward. Writing in the journal Medicine, the research team concluded that L. reuteri Protectis was considered the most effective treatment from a choice that included, drugs, herbs, acupuncture, massage, manipulation and reassurance/education. The team, based at the UNITEC Technological University of Mexico placed specialised infant formulas (partially hydrolysed and whey-protein derivate), as the next best treatment. Commenting on the systematic review that involved 32 trials and a networking meta-analysis approach, lead author Dr Pedro Gutiérrez-Castrellón, “supported the use of L. reuteri DSM 17938 as the most evidence-based significant intervention to reduce the duration of crying time in infant colic”. Second meta-analysesConclusions reached in Dr Gutiérrez-Castrellón’s study were mirrored by another meta-analysis that combined raw data from four double-blind trials. All studies enrolled a total of 345 infants with colic that were administered with L. reuteri Protectis (manufactured by BioGaia) in the same dose (0.2 × 108 colony-forming units per drop, 5 drops orally per day), with control groups receiving the same placebo (maltodextrin in oil suspension). The measured outcomes were of infant crying and/or fussing duration and treatment success at 21 days. Led by Dr Valerie Sung, a consultant paediatrician and postdoctoral research fellow at Murdoch Children's Research Institute, the paper concluded that L. reuteri Protectis was effective and can be recommended for breastfed infants with colic. However, the team—some of which disclosed personal fees from BioGaia outside the submitted work—acknowledged data was lacking for the strain’s efficacy in formula-fed infants.  IPA World Congress + Probiota 2018 The rapidly evolving universe of probiotics, prebiotics and the microbiome will be discussed in-depth at the upcoming IPA World Congress + Probiota 2018 in Barcelona on February 7-9. From microbiome advances, to start-up game changers, market stats, crucial clinical science and regulatory knowledge, this is a congressional must-have. Will you be joining your peers in one of Europe’s great cities? Probiotics: The real deal?Despite the showing of L. reuteri Protectis in these studies, the evidence of probiotic intervention in conditions like colic remain finally balanced. Dr Sung was the lead author in another study that declared a lack of evidence to support its use in a sample of breastfed infants and formula fed infants with colic. These findings differed from previous smaller trials of selected populations and the team, writing in the British Medical journal, “recommended caution in formulating recommendations regarding use of L reuteri DSM 17938 for reducing crying or fussing in breastfed, and particularly in formula fed, infants with colic.” Source: Medicine Source: Pediatrics Does BioGaia work for colic?It's been proven to help reduce and prevent episodes of crying in babies suffering from colic and other digestive discomforts. It's effective and safe to use in infants from newborn and onwards to soothe most common tummy issues like colic, regurgitation, constipation and infectious diarrhea.
Is BioGaia safe for newborns?Clinical studies have shown that BioGaia Protectis drops are safe to give from day of birth.
Do probiotics help with infant colic?Although probiotics make little or no difference to the occurrence of infantile colic, they may reduce crying time and there were no safety concerns.
How long does it take for BioGaia drops to work?How long does it take to feel the effects of taking Biogaia Drops? Normally, you should notice the effects within a few days. While people who are healthy may not experience any differences, those taking L. reuteri because of a digestive system disturbance may notice an improvement in symptoms after 3-4 days.
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Biogaia probiotic drops for infant colic relief
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